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A new controlled human trial: Creatine + gut bacteria may treat depression

New human research reveals how gut bacteria and creatine may restore brain energy and improve depression. If you have or know ...
Health Affairs

The Camden Coalition Care Management Program Improved Intermediate Care Coordination: A Randomized Controlled Trial

When a randomized evaluation finds null results, it is important to understand why. We investigated two very different explanations for the finding from a randomized evaluation that the Camden ...
ascopubs.org

Effect of Adding Electroacupuncture to Standard Triple Antiemetic Therapy on Chemotherapy-Induced Nausea and Vomiting: A Randomized Controlled Clinical Trial

Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting: Final Results of a Randomized, Placebo-Controlled, Phase II/III Trial From March 2022 to December 2023, a ...
ascopubs.org

Effect of an Invitation or the Effect of Participation: What Should Randomized Controlled Trials of Cancer Screening Examine?

Personalized Chemotherapy on the Basis of Tumor Marker Decline in Poor-Prognosis Germ-Cell Tumors: Updated Analysis of the GETUG-13 Phase III Trial Earlier detection of cancer offers an opportunity to ...
BMJ Open

Practical guide for determining whether healthcare providers are research participants in cluster randomised trials

Introduction In cluster randomised trials (CRT), groups (rather than individuals) are randomised to intervention and control conditions. Since the publication of the Ottawa Statement on the Ethical ...
STAT

Keeping pregnant participants out of medical research is more dangerous than including them

“Well, we don’t have as much evidence as we would like on steroid use during pregnancy,” the obstetrician warned my co-author, Natalia Emanuel, as she wrote a prescription for inhaled corticosteroids ...