Novel Gene and Variant Discovery in Human Genetic Disorders: From Coding and Non-Coding RNA variants
Rapid advances in sequencing technologies have transformed our ability to diagnose human genetic disorders, yet many patients still lack a molecular ...
It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...
Interesting Engineering on MSN
Scientists identify a non-coding gene that directly controls how big cells grow
The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.
What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...
Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human ...
A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...
But only a tiny percentage of our DNA – around 2% – contains our 20,000-odd genes. The remaining 98% – long known as the non-coding genome, or so-called ‘junk’ DNA – includes many of the switches that ...
News Medical on MSN
Breast cancer hijacks immune alarm: turning defense into cancer-fueling inflammation
Researchers uncover a cunning new trick by which breast cancer cells evade immune attack. While the cGAS-STING pathway normally detects cytosolic DNA and activates anti-tumor immunity via ...
A father’s plastic exposure could significantly induce metabolic disorders like diabetes in offspring. Limiting the plastic ...
Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...
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